
徐旭林,博士,副教授。2004、2009年分別獲華中科技大學(xué)碩士、博士學(xué)位,2007年至2009年在美國(guó)弗吉尼亞州立大學(xué)做訪問(wèn)學(xué)者。現(xiàn)主要從事藥理學(xué)教學(xué)和科研。
主要研究方向:精神神經(jīng)藥理
主持的科研項(xiàng)目:
1.國(guó)家自然科學(xué)基金:
kcnq2 磷酸化水平調(diào)控海馬神經(jīng)元m(kv7)通道活動(dòng)依賴性轉(zhuǎn)運(yùn)
代表性論文:
1. xu x, jiang m, wang y, smith t, baumgarten cm, wood ma, tseng gn.long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model.plos one. 2010 apr 13;5(4):e10140.
3. jiang m, xu x, wang y, toyoda f, liu xs, zhang m, robinson rb, tseng gn.. dynamic partnership between kcnq1 and kcne1 and influence on cardiac iks current amplitude by kcne2. j biol chem. 2009 ;284(24):16452-62.
2. xu x, recanatini m, roberti m, tseng gn. probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (ns1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1h-isoindol-5-ylamino]-nicotinic acid (pd307243). mol. pharmacol. 2008 jun; 73(6):1709-21.
4. xu x, jiang m, hsu kl, zhang m, tseng gn. kcnq1 and kcne1 in the iks channel complex make state-dependent contacts in their extracellular domains. j gen physiol. 2008 jun; 131(6):589-603.