
馬嶸
2009年獲博士學(xué)位,現(xiàn)為華中科技大學(xué)同濟(jì)醫(yī)學(xué)院藥理學(xué)系副教授,碩士研究生導(dǎo)師。2012-2013年在美國(guó)內(nèi)布拉斯加醫(yī)學(xué)中心神經(jīng)藥理系從事博士后研究工作;2013-2014年在美國(guó)哈佛大學(xué)醫(yī)學(xué)院布萊恩婦女醫(yī)院神經(jīng)疾病研究中心從事博士后工作。主要研究方向?yàn)樯窠?jīng)變性性疾病(Alzheimer‘s disease,Parkinson’s disease)的發(fā)病機(jī)制。
參與的課題:
Wnt信號(hào)通路失活在多巴胺能神經(jīng)元變性中的作用研究(國(guó)家自然科學(xué)基金青年基金,項(xiàng)目負(fù)責(zé)人)
補(bǔ)體C3/C3aR過(guò)度活化在Tau蛋白介導(dǎo)的神經(jīng)退行性疾病中的作用及機(jī)制研究 (國(guó)家自然科學(xué)基金面上項(xiàng)目,參與)
調(diào)節(jié)鞘氨醇激酶活性對(duì)阿爾茨海默病的保護(hù)作用及其機(jī)制研究(國(guó)家自然科學(xué)基金面上項(xiàng)目,參與)
FKBP12.6蛋白在他克莫司對(duì)腦缺血/再灌損傷保護(hù)中的重要作用(國(guó)家自然科學(xué)基金青年基金,參與)
薟草內(nèi)生真菌抗腫瘤活性次生代謝產(chǎn)物的研究 (國(guó)家自然科學(xué)基金面上項(xiàng)目,參與)
代表性期刊論文:
1. Rong Ma, Lu Yang, Fang Niu, Shilpa Buch, HIV Tat-Mediated Induction of Human Brain Microvascular Endothelial Cell Apoptosis Involves Endoplasmic Reticulum Stress and Mitochondrial Dysfunction. Molecular Neruobiology, 2016 Jan;53(1):132-42. doi: 10.1007/s12035-014-8991-3. [IF=5.286]
2. Honghong Yao, Rong Ma (co-first author), Lu Yang, Guoku Hu, Xufeng Chen, Ming Duan, Yeonhee Kook, Fang Niu, Ke Liao, Minggui Fu, Gang Hu, Pappachan Kolattukudy, Shilpa Buch* MiR-9 promotes microglial activation by targeting MCPIP1. Nature Communications, 2014 Jul 14;5:4386. doi: 10.1038/ncomms5386 [IF=10.8]
3. Rong Ma, Chengfang Huang, Jin Hu, Min wang, Jizhong xiang, Gang Li,JAK2/STAT5/Bcl-xL signaling is essential for erythropoietin-mediated protection against PC12 cells apoptosis induced by A?25-35. British Journal of Pharmacology, 171: 3234–3245, 2014 [IF=5.0]
4. Yaoyan Dun,Yang Yang, Zhengguo Xiong, Mei Feng, Yuan Zhang, Jizhou Xiang, Gang Li , Rong Ma. Induction of Dkk1 contributes to the neurotoxicity of MPP++ in PC12 cells via inhibition of the canonical Wnt signaling pathway .Neuropharmacology, 67:168-175,2013. [IF=4.8]
5. Yaoyan Dun,Gang Li,Yang Yang, Zhengguo Xiong, Mei Feng, Yuan Zhang, Jizhou Xiang, Rong Ma. Inhibition of the canonical Wnt pathway by Dickkopf-1 contributes to the neurodegeneration in 6-hydroxydopamine-lesioned rats Neuroscience Letter, 525(2),83-88,2012. [IF=2.0]