
吳萍,女,博士,副教授,碩士生導(dǎo)師,
· 1991.9-1996.6,同濟醫(yī)科大學(xué),臨床2系,本科學(xué)歷/學(xué)士學(xué)位,
· 1999.9-2002.6,華中科技大學(xué)同濟醫(yī)學(xué)院,病理生理學(xué)系,碩士
· 2005.9-2008.6,華中科技大學(xué)同濟醫(yī)學(xué)院,病理生理學(xué)系,博士
研究工作經(jīng)歷
· 1996.7-今,華中科技大學(xué)同濟醫(yī)學(xué)院,病理生理學(xué)系,助教、講師、副教授
· 2007.9年-2009.9,美國utah大學(xué),呼吸內(nèi)科,聯(lián)合培養(yǎng)博士,博士后
科研成果
主持課題:
國家自然科學(xué)基金面上項目:以缺氧誘導(dǎo)因子為靶點研究脂氧素“再教育”腫瘤相關(guān)巨噬細胞的機制 2013年no.81272313
國家自然科學(xué)基金青年基金:《幾種抗炎中西藥對巨噬細胞ho/co調(diào)控機制的異同性研究》2002年no.30100226
華中科技大學(xué)校基金:《nrf2激活在lipoxin對小鼠急性肺損傷保護作用中的角色初探》2009年no.2009jc019
獲獎情況:
2005年 論文《幾種抗炎中藥的藥理機制與其促炎癥緩解作用的關(guān)系研究》獲得中國病理生理學(xué)會炎癥發(fā)熱感染低溫專業(yè)委員會和中醫(yī)病理生理專業(yè)委員會第十屆全國學(xué)術(shù)會議青年優(yōu)秀論文二等獎 (獲獎?wù)撸簠瞧迹粚?dǎo)師:葉篤筠)
已發(fā)表論著:
1. wu, p., cancer related inflammation and tumor angiogenesis, in tumor angiogenesis, s. ran, editor. 2012, intech. p. 197-212.
(http://www.intechopen.com/articles/show/title/cancer-related-inflammation-and-tumor-angiogenesis)
已發(fā)表相關(guān)論文:
1. chen y, hao h, he s, cai l, li y, hu s, ye d, hoidal j, wu p(corresponding), chen x(corresponding). lipoxin a4 and its analogue suppress the tumor growth of transplanted h22 in mice: the role of antiangiogenesis. mol cancer ther. 2010;9(8):2164-74.
2. xu lm, jin sw, zhou xy, wu p(corresponding), li ys, zhang l, lin yy, chen y, ye dy. effects of exogenous annexin-1 on lipopolysaccharide-induced proliferation and reactive oxygen species production partially through modulation of crac channels but independent of nf-kappab pathway. inflamm res. 2009;58(12):921-30.
3. li g, wu p(corresponding), xu y, yu y, sun l, zhu l, ye d. the effect of lipoxin a4 on the interaction between macrophage and osteoblast: possible role in the treatment of aseptic loosening. bmc musculoskelet disord. 2009 jun 2;10:57.
4. wu l, miao s, zou lb, wu p, hao h, et al. lipoxin a4 inhibits 5-lipoxygenase translocation and leukotrienes biosynthesis to exert a neuroprotective effect in cerebral ischemia/reperfusion injury.j mol neurosci. 2012, 48(1):185-200.
5. liu s, wu p, ye dy, huang y, zhou x, li y, cai l. effects of lipoxin a(4) on cocl(2)-induced angiogenesis and its possible mechanisms in human umbilical vein endothelial cells. pharmacology. 2009;84(1):17-23.
6. hao h, liu m, wu p, cai l, tang k, yi p, li y, chen y, ye d. lipoxin a(4) and its analog suppress hepatocellular carcinoma via remodeling tumor microenvironment. cancer lett. 2011;309(1):85-94.
7. pang h, yi p, wu p, liu z, liu z, gong j, hao h, cai l, ye d, huang y. effect of lipoxin a4 on lipopolysaccharide-induced endothelial hyperpermeability. scientific world journal. 2011;11:1056-67.
8. ismail s, sturrock a, wu p, cahill b, norman k, huecksteadt t, sanders k, kennedy t, hoidal j. nox4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of tgf-β1 and igfbp-3. am j physiol lung cell mol physiol. 2009;296(3):l489-99.
9. zhou xy, li ys, wu p, wang hm, cai zy, xu fy, ye dy. lipoxin a(4) inhibited hepatocyte growth factor-induced invasion of human hepatoma cells. hepatol re. 2009;39(9): 921- 30.
10. wu l, miao s, zou lb, wu p, hao h, et al. lipoxin a4 inhibits 5-lipoxygenase translocation and leukotrienes biosynthesis to exert a neuroprotective effect in cerebral ischemia/reperfusion injury.j mol neurosci. 2012, 48(1):185-200.
11. li y, cai l, wang h, wu p, gu w, chen y, hao h, tang k, yi p, liu m, miao s, ye d. pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2. oncogene. 2011;30(36):3887-99.
12. 苗森,郝華, 吳萍 (通訊作者). 血紅素氧合酶-1與中藥抗炎抗氧化作用的研究進展. 中華臨床醫(yī)師雜志. 2011;5(18):5406-5409.
13. 連展,吳萍 (通訊作者),周靜. 耐多藥結(jié)核病患者外周血腫多藥耐藥相關(guān)跨膜轉(zhuǎn)運蛋白的表達. 中華結(jié)核和呼吸雜志.2011;34(7):520-523.
14. 周曉燕,徐方云,蔡震宇,王紅梅,祝子瑞,吳萍,葉篤筠. 脂氧素a4對脂多糖誘導(dǎo)巨噬細胞氧化損傷的影響. 細胞生物學(xué)雜志. 2009;31(3): 433-436.
15. 龐花艷,黃引平,劉忠杰,易攀,龔建明,郝華,吳萍,周潔,蔡蕾,黃艷君,葉篤筠,王振煥. 脂氧素對脂多糖誘導(dǎo)的臍靜脈內(nèi)皮細胞通透性的影響 .中華婦產(chǎn)科雜志. 2011;46(3):199-204.
16. 周曉燕,王紅梅,蔡震宇,徐方云,黃永紅,朱俊,吳萍,葉篤筠. 脂氧素a4對肝細胞生長因子誘導(dǎo)hepg2肝癌細胞血管生成相關(guān)細胞因子表達的影響. 中國病理生理雜志. 2011; 27(2): 300-303.
17. 劉忠杰, 黃引平, 易攀, 龐花艷, 龔建明, 黃艷君, 周潔, 吳萍, 葉篤筠, 郝華. 脂氧素對脂多糖誘導(dǎo)的人臍靜脈內(nèi)皮細胞氧化應(yīng)激反應(yīng)的影響.中華婦產(chǎn)科雜志. 2010;45(11): 848-853.
會議摘要:
1. 郝華,劉淼,吳萍(通訊作者),葉篤筠. 脂氧素a4通過重塑腫瘤微環(huán)境抑制前列腺癌. 中國病理生理雜志. 2010;26(10):2020.