朱鈴強(qiáng)，三級(jí)教授，博士生導(dǎo)師，耶魯大學(xué)博士后、華中學(xué)者特聘崗、國(guó)際雜志Journal of Alzheimer’s Disease（影響因子3.9）Senior Editor、全國(guó)百篇優(yōu)秀博士論文提名獎(jiǎng)獲得者，湖北省杰出青年基金獲得者，2016湖北省科協(xié)創(chuàng)新創(chuàng)業(yè)人才工程，華中科技大學(xué)中加神經(jīng)疾病分子生物學(xué)聯(lián)合平臺(tái)中方負(fù)責(zé)人，華中科技大學(xué)首屆學(xué)術(shù)前沿青年團(tuán)隊(duì)負(fù)責(zé)人，首屆學(xué)術(shù)新人獎(jiǎng)獲得者。目前研究方向：阿爾茨海默病的早期防治措施研究。承擔(dān)國(guó)家自然科學(xué)基金青年項(xiàng)目、面上項(xiàng)目、動(dòng)物模型專(zhuān)項(xiàng)、重大計(jì)劃培育項(xiàng)目、國(guó)際合作（中德，中加）、海外港澳臺(tái)基金共10項(xiàng)，科技部重大國(guó)際合作專(zhuān)項(xiàng)一項(xiàng)、美國(guó)阿爾茨海默病協(xié)會(huì)（Alzheimer Association）新研究者基金一項(xiàng)。目前以通訊作者和第一作者發(fā)表SCI論文48篇，其中包括Nature Neuroscience、Neuron、Mol Psychiatry、Nature Communications、Biological Psychiatry、Cell Death & Differ.、Mol Therapy、J Neurosci（6篇）、Aging Cell、Mol Neurobiol、Neurobiol Aging、J Neurochem等國(guó)際知名雜志，長(zhǎng)期擔(dān)任國(guó)家自然科學(xué)基金委一審專(zhuān)家，意大利國(guó)家自然科學(xué)基金衰老組一組組長(zhǎng)。

聯(lián)系方式

基礎(chǔ)醫(yī)學(xué)院二號(hào)教學(xué)樓八樓803辦公室

電話：13308657291

Email：zhulq@mail.hust.edu.cn

QQ: 307728280

工作簡(jiǎn)介

主要從事阿爾茨海默病（Alzheimer’s disease, AD）發(fā)病的分子機(jī)制及防治措施的研究。該病是一種高發(fā)于老齡人群的神經(jīng)退行性疾病，AD患者的主要臨床表現(xiàn)為學(xué)習(xí)記憶能力漸進(jìn)性減退，從而給其生活帶來(lái)了極大的不便，也給家庭和社會(huì)造成了極大的經(jīng)濟(jì)和精神負(fù)擔(dān)。目前認(rèn)為，AD早期突觸可塑性的紊亂是引起AD患者學(xué)習(xí)記憶障礙的主要原因，但其機(jī)制和可能的保護(hù)措施暫不明了。申請(qǐng)人針對(duì)AD突觸病變及神經(jīng)環(huán)路異常的發(fā)生發(fā)展的機(jī)制展開(kāi)了一系列的工作并取得了一定的科研成果，主要包括：
1，利用光遺傳學(xué)和轉(zhuǎn)基因技術(shù)，首次發(fā)現(xiàn)內(nèi)嗅皮層II層的島細(xì)胞可以直接投射到海馬CA1的小清蛋白（PV）陽(yáng)性的抑制性神經(jīng)元形成ECII_PN–CA1 _PV神經(jīng)環(huán)路，并且發(fā)現(xiàn)其功能在AD早期明顯降低，從而引起CA1腦區(qū)興奮/抑制失平衡并參與AD早期的學(xué)習(xí)記憶障礙；

2，系統(tǒng)研究了一系列miRNA在AD發(fā)病中的作用，如miR-124可以明顯下調(diào)Zif268的表達(dá)，進(jìn)而抑制小鼠的學(xué)習(xí)記憶和社會(huì)交往能力；miR-218分子可以特異的作用于PTPa，而后者則可以特異性調(diào)控tau蛋白磷酸化相關(guān)的激酶GSK-3及酯酶PP2A的酪氨酸磷酸化，從而打破激酶和酯酶的平衡并且引起tau過(guò)度磷酸化和聚集的病變；

3，系統(tǒng)地研究并證明了糖原合酶激酶 3 激活在阿爾茨海默病突觸病變形成中的重要作用，并闡明了其作用機(jī)理是通過(guò)磷酸化突觸前 P/Q 型鈣通道阻礙了突觸前囊泡的釋放，從而抑制長(zhǎng)時(shí)程增強(qiáng)（LTP）的形成。并且針對(duì)糖原合酶激酶 3 激活探討了一系列的保護(hù)措施。

發(fā)表論文（*通訊作者）

1. Li X, Chen W, Pan K, Li H, Pang P, Guo Y, Shu S, Cai Y, Pei L, Liu D, Afewerky HK, Tian Q, Zhu LQ*, Lu Y*. Serotonin receptor 2c-expressing cells in the ventral CA1 control attention via innervation of the Edinger-Westphal nucleus. Nat Neurosci. 2018 Aug 13.

2. Li K, Wei Q, Liu FF, Hu F, Xie AJ, Zhu LQ*, Liu D*. Synaptic Dysfunction in Alzheimer's Disease: Aβ, Tau, and Epigenetic Alterations. Mol Neurobiol. 2018 55:3021-3032.

3. Wang X, Liu D, Huang HZ, Wang ZH, Hou TY, Yang X, Pang P, Wei N, Zhou YF, Dupras MJ, Calon F, Wang YT, Man HY, Chen JG, Wang JZ, Hébert SS, Lu Y, Zhu LQ*. A Novel MicroRNA-124/PTPN1 Signal Pathway Mediates Synaptic and Memory Deficits in Alzheimer's Disease. Biol Psychiatry. 2018:83;395-405. (Highlight in this issue and commentary by Dr. Wang-Xia Wang)

4. Yang X, Yao C, Tian T, Li X, Yan H, Wu J, Li H, Pei L, Liu D, Tian Q, Zhu LQ, Lu Y. Synaptic mechanism in Alzheimer's disease: a selective degeneration of an excitatory synaptic pathway in the CA1 hippocampus that controls spatial learning and memory in Alzheimer's disease. Mol Psychiatry. 2018 Feb;23(2):167.(Image)

5. Yang X, Yao C, Tian T, Li X, Yan H, Wu J, Li H, Pei L, Liu D, Tian Q, Zhu LQ*, Lu Y*. A novel mechanism of a memory loss in Alzheimer’s disease mice via degeneration of entorhinal-CA1 synapses. Mol Psychiatry. 2018: 23(2):199-210. (IF=13.7)

6. Wang DQ, Fu P, Yao C, Zhu LS, Hou TY, Chen JG, Lu Y, Liu D*, Zhu LQ*. Long non-coding RNAs, novel culprits or bodyguards in neu-rodegenerative diseases. Molecular Therapy-Nucleic Acid. 2018, 10(2):269-276.

7. Zhu H, Yan H, Tang N, Li X, Pang P, Li H, Chen W, Guo Y, Shu S, Cai Y, Pei L, Liu D, Luo MH, Man H, Tian Q, Mu Y*, Zhu LQ*, Lu Y*. Impairments of spatial memory in an Alzheimer’s disease model via degeneration of hippocampal cholinergic synapses. Nat Commun. 2017, Nat Commun. 2017 Nov 22;8(1):1676.

8. Wu L, Meng J, Shen Q, Zhang Y, Pan S, Chen Z, Zhu LQ, Lu Y, Huang Y, Zhang G. Caffeine inhibits hypothalamic A(1)R to excite oxytocin neuron and ameliorate dietary obesity in mice. Nat Commun. 2017 Jun 27;8:15904.

9. Yang S, Jin H, Zhu Y, Wan Y, Opuku EN, Zhu LQ*, Hu B*. Diverse Functions and Mechanisms of Pericytes in Ischemic Stroke. Current Neuropharmacology, In press

10. Liu D, Tang H, Li XY, Deng MF, Wei N, Wang X, Zhou YF, Wang DQ, Fu P, Wang JZ, Hebert SS, Chen JG, Lu Y, Zhu LQ*. Targeting the HDAC2/HNF-4A/miR0101b/AMPK pathway rescues tauopathy and dendritic abnormalities in Alzheimer’s disease Molecular Therapy. 2017 Mar 1;25(3):752-764 (IF=6.938)

11. An TH, He QW, Xia YP, Chen SC, Baral S, Mao L, Jin HJ, Li YN, Wang MD, Chen JG, Zhu LQ*, Hu B*. MiR-181b Antagonizes Atherosclerotic Plaque Vulnerability Through Modulating Macrophage Polarization by Directly Targeting Notch1. Mol Neurobiol. 2016 Oct 8.

12. Shu S, Zhu HZ, Tang N, Chen W, Li X, Li H, Pei L, Liu D, Mu Y, Tian Q, Zhu LQ*, Lu Y*. Selective Degeneration of Entorhinal-CA1 Synapses in Alzheimer’s Disease via Activation of DAPK1. J Neurosci. 2016 Oct 19;36(42):10843-10852 (IF=5.9)

13. Liu YS, Dai X, Wu W, Yuan FF, Gu X, Chen JG, Zhu LQ*, Wu J*. The Association of SNAP25 Gene Polymorphisms in Attention Deficit/Hyperactivity Disorder: a Systematic Review and Meta-Analysis. Mol Neurobiol. 2017 Apr;54(3):2189-2200. (IF=5.3)

14. Xie AJ, Liu EJ, Huang HZ, Hu Y, Li K, Lu Y, Wang JZ*, Zhu LQ*. Cnga2 Knockout Mice Display Alzheimer's-Like Behavior Abnormities and Pathological Changes. Mol Neurobiol. 2016 Sep;53(7):4992-9.

15. Xiong YS, Liu FF, Liu D, Huang HZ, Wei N, Tan L, Chen JG, Man HY, Gong CX, Lu Y, Wang JZ, Zhu LQ*. Opposite effects of two estrogen receptors on tau phosphorylation regulation through disparate effects on the miR-218/PTPA pathway. Aging Cell, 2015, 14: 867–877.

16. Wang MD, Wang Y, Xia YP, Dai JW, Gao L, Wang SQ, Wang HJ, Mao L, Li M, Yu SM, Tu Y, He QW, Zhang GP, Wang L, Xu GZ, Xu HB, Zhu LQ*, Hu B*. High Serum MiR-130a Levels Are Associated with Severe Perihematomal Edema and Predict Adverse Outcome in Acute ICH. Mol Neurobiol. 2016 Mar;53(2):1310-21.

17. Li K, Liu FF, He CX, Huang HZ, Xie AJ, Hu F, Liu D, Wang JZ*, Zhu LQ*. Olfactory Deprivation Hastens Alzheimer-Like Pathologies in a Human Tau-Overexpressed Mouse Model via Activation of cdk5. Mol Neurobiol. 2016 Jan;53(1):391-401.

18. Liu D, Wei N, Man HY, Lu Y*, Zhu LQ*,Wang JZ*. The MT2 receptor stimulates axonogenesis and enhances synaptic transmission by activating Akt signaling. Cell Death & Differentiation. 2015 Apr;22(4):583-96.

19. Hu J, Huang HZ, Wang X, Xie AJ, Wang X, Liu D, Wang JZ*, Zhu LQ*. Glycogen synthase kinase-3 links the olfactory deficit to hippocampal impairments. Mol Neurobiol. 2015 Dec;52(3):1601-17.

20. Liu DY, Shen XM, Yuan FF, Guo OY, Zhong Y, Chen JG, Zhu LQ* Wu J*. The physiology of BDNF and its relationship with ADHD. Mol Neurobiol. 2015 Dec;52(3):1467-76.

21. Pei L, Shang Y, Jin H, Wang S, Wei N, Yan H, Wu Y, Yao C, Wang X, Zhu LQ*, Lu Y*. DAPK1-p53 Interaction Converges Necrotic and Apoptotic Pathways of Ischemic Neuronal Death. J Neurosci. 2014 May 7;34(19):6546-56.

22. Chen Y, Wang B, Liu D, Li JJ, Xue Y, Sakata K, Zhu LQ, Heldt SA, Xu H, Liao FF. Hsp90 chaperone inhibitor 17-AAG attenuates Aβ-induced synaptic toxicity and memory impairment. J Neurosci. 2014 Feb 12;34(7):2464-70.

23. Wang X, Wang LP, Tang H, Shan WY, Wang X, Liu D, Wu YY, Tian Q, Wang JZ*, Zhu LQ*. Acetyl-l-carnitine rescues scopolamine-induced memory deficits by restoring insulin-like growth factor II via decreasing p53 oxidation. Neuropharmacology. 2014, 76(A) :80-87.

24. Wu YY, Wang X, Tan L, Liu D, Liu XH, Wang Q, Wang JZ*, Zhu LQ*. Lithium Attenuates Scopolamine-Induced Memory Deficits with Inhibition of GSK-3β and Preservation of Postsynaptic Components. J Alzheimers Dis. 2013, 37(3):515-527.

25. Tang H, Shen N, Jin HJ, Liu D*, Miao X*, Zhu LQ*. GSK-3β polymorphism discriminates bipolar disorder and schizophrenia: a systematic meta-analysis. Molecular Neurobiology. 2013,48(3):404-411.

26. Xiong YS, Wang DL, Tan L, Wang X, Chen LM, Gong CX, Wang JZ*, Zhu LQ*. Inhibiton of glycogen synthase kinase-3 reverses tau hyperphosphorylation induced by Pin1 downregulation. CNS & Neurological Disorders - Drug Targets. 2013, 12(3):436-443.

27. Zhao K, Wen R, Wang X, Pei L, Yang Y, Shang Y, Bazan N, Zhu LQ*, Tian Q*, Lu Y*. EPAC Inhibition of SUR1 Receptor Increases Glutamate Release and Seizure Vulnerability. J Neurosci. 2013,33(20):8861-8865. (IF=7.271)

28. Peng CX, Hu J, Liu D, Hong XP, Wu YY, Zhu LQ*, Wang JZ*. Disease-modified GSK-3b intervention by melatonin arrests the pathology and memory deficits in Alzheimer’s animal model. Neurobiology of Aging. 2013, 34(6):1555-1563. (IF=6.189)

29. Qu M, Jiang J, Liu XP, Tian Q, Chen LM, Yin G, Liu D, Wang JZ*, Zhu LQ*. Reduction and the intracellular translocation of EphB2 in Tg2576 mice and the effects of b-amyloid. Neuropathology and Applied Neurobiology. 2013 Oct;39(6):612-22. (IF=4.837)

30. Zhong R, Yang B, Tang H, Zou L, Song R, Zhu LQ*, Miao XP*. Meta-analysis of the association between DCDC2 polymorphisms and risk of Dyslexia. Molecular Neurobiology. 2013;47(1):435-442. (IF=5.735)

31. Wang X, Wang ZH, Wu YY, Tang H, Tan L, Wang X, Gao XY, Xiong YS, Liu D*, Wang JZ, Zhu LQ*. Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathsway. Molecular Neurobiology. 2013;47(1):373-381. (IF=5.735)

32. Wang SH, Liao XM, Liu D, Hu J, Yin YY, Wang JZ*, Zhu LQ*. NGF Promotes Long-term Memory Formation by Activating Poly(ADP-ribose)polymerase-1. Neuropharmacology. 2012;63(6):1085-1092 (IF=4.8)

33. Wu J, Xiao H, Sun H, Zou L, Zhu LQ*. Role of dopamine receprots in ADHD: a systematic meta-analysis. Molecular Neurobiology. 2012; 45(3):605-20. (IF=5.735)

34. Yang Y, Shu X, Liu D, Shang Y, Wu Y, Pei L, Xu X, Tian Q, Zhang J, Qian K, Wang YX, Petralia RS, Tu WH, Zhu LQ*, Wang JZ*, Lu Y*. EPAC Null Mutation Impairs Learning and Social Interactions via Aberrant Regulation of miR-124 and Zif268 Translation. Neuron, 2012;73(4):774-788. (IF=14.027)

35. Liao K, Liu D, Zhu LQ*. Enriched odor exposure decrease tau phosphorylation in the rat hippocampus and cortex. Neurosci Lett. 2012;507(1):22-26. (IF=2.055)

36. Hu J, Wang X, Liu D, Wang Q, Zhu LQ*. Olfactory deficits induce neurofilament hyperphosphorylation. Neurosci Lett. 2012; 506(2):180-183. (IF=2.055)

37. Zhou P, Chen Z, Zhao N, Liu D, Hu J, Guo ZY, Wang Q, Wang JZ*, Zhu LQ*. Acetyl-L-Carnitine attenuates homocysteine-induced Alzheimer-like histopathological and behavioral abnormalities. Rejuvenation Research. 2011, 14(6): 669-679. (IF=4.225)

38. Jiang X, Tian Q, Wang Y, Zhou XW, Xie JZ, Wang JZ, Zhu LQ*. Acetyl-L-Carnitine ameliorates spatial memory deficits induced by inhibition of phosphoinositol-3 kinase and protein kinase C. J Neurochem. 2011;118(5):864-878.(IF=4.337)

39. Chen LM, Xiong YS, Kong FL, Qu M, Wang Q, Chen XQ, Wang JZ*, Zhu LQ*. Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling. J Neurochem. 2012 Jan;120(1):157-64 (IF=4.337)

40. Liu D, Zheng HY, Luo ZZ, Wang Q, Zhu LQ*. Effect of PP-2A on neurite outgrowth in neuronal cells. In Vitro Cell Dev-AN, 2010, 46(8): 702-707 (IF=1.312)

41. Zhu LQ, Liu D, Hu J, Cheng J, Wang SH, Wang Q, Wang F, Chen JG, Wang JZ. GSK-3b inhibits presynaptic vesicle exocytosis by phosphorylating P/Q-type calcium channel and interrupting SNARE complex formation. J Neurosci. 2010;30(10):3624-33. (IF:7.49)

42. Zhu LQ, Zheng HY, Peng CX, Liu D, Li HL, Wang Q, Wang JZ. Protein phosphatase 2A facilitates functional axonogenesis by dephosphorylating CRMP2. J Neurosci. 2010;30(10):3839-48. (IF:7.49)

43. Yin YY, Liu H, Liu Z, Cong XB, Wang Q, Wang JZ*, Zhu LQ*. Acetyl-L-carnitine attenuates okadaic acid induced tau hyperphosphorylation and spatial memory impairment in rats. J Alzheimer’s Disease 2010;19(2):735-46. (IF=5.0)

44. Shi HR, Zhu LQ*, Wang SH, Liu XA, Tian Q, Zhang Q, Wang Q, Wang JZ*. (2008). 17 β-estradiol attnuates glycogen synthase kinase-3β activation and tau hyperphosphorylation in Akt-independent manner. J Neural Transmission 115(6):879-888. (IF:2.938)

45. Liu XA, Zhu LQ*, Zhang Q, Shi HR, Wang SH, Wang Q, Wang JZ*. (2008). Estradiol attenuates tau hyperphosphorylation induced by upregulation of protein kinase-A. Neurochemical Res 2008 Sep;33(9):1811-20. (IF:2.18)

46. Zhu LQ, Wang SH, Liu D, Yin YY, Tian Q, Wang XC, Wang Q, Chen JG, Wang JZ (2007). Activation of glycogen synthase kinase-3 inhibits long term potentiation with synapse-associated impairments. J Neurosci 27:12211-12220. (IF:7.49)

47. Wang SH, Zhu LQ, Wang Q, et al. (2007). Inhibition of Melatonin Biosynthesis Induces Neurofilament Hyperphosphorylation with Activation of Cyclin-dependent Kinase 5. Neurochem Res 32(8):1329-1335. (IF:2.18)

48. Zhu LQ, Wang SH, Ling ZQ, et al. (2004). Effect of inhibiting melatonin biosynthesis on    spatial memory retention and tau phosphorylation in rat. J Pineal Res 37 (2):71-77. (IF:4.228)

承擔(dān)項(xiàng)目

2008年，國(guó)家自然科學(xué)基金青年基金，30800342，糖原合酶激酶3在阿爾茨海默病突觸病變中的作用和機(jī)制，20萬(wàn)元，負(fù)責(zé)人 2009.1.1-2011.12.31

2009年，國(guó)家自然科學(xué)基金面上基金，30971478，雌激素受體beta在衰老相關(guān)記憶障礙中的作用和機(jī)制，31萬(wàn)元，負(fù)責(zé)人 2010.1.1-2012.12.31

2009年，華中科技大學(xué)首屆學(xué)術(shù)新人獎(jiǎng)人才基金，20萬(wàn)，負(fù)責(zé)人

2010年，教育部新世紀(jì)優(yōu)秀人才支持計(jì)劃，NCET-10-0421，神經(jīng)細(xì)胞粘附分子唾液酸化失調(diào)引起阿爾茨海默病突觸病變的分子機(jī)理，50萬(wàn)，負(fù)責(zé)人 2011.5-2014.4

2011年，美國(guó)阿爾茨海默協(xié)會(huì)基金，NIRG-11-205737，Role of EphB2

signal in tau pathology in Alzheimer's Disease，10萬(wàn)美金，負(fù)責(zé)人（目前中國(guó)獲得該基金的只有三人） 2011.10-2013.9

2011年，國(guó)家自然科學(xué)基金重大計(jì)劃，91132725, 嗅覺(jué)環(huán)境變化對(duì)內(nèi)嗅皮層-海馬環(huán)路功能的影響及在阿爾茨海默病樣記憶障礙中的作用80萬(wàn)元，負(fù)責(zé)人 2012.1.1-2014.12.31

2012年，中國(guó)科技部-加拿大國(guó)際合作專(zhuān)項(xiàng)基金，2011DFG33250，運(yùn)用新型基因技術(shù)探索糖原合酶激酶3在腦功能和疾病中作用的合作研究，170萬(wàn)元，負(fù)責(zé)人 2012.4-2015.3

2013年，國(guó)家自然科學(xué)基金委員會(huì)（NSFC）與加拿大魁北克醫(yī)學(xué)研究基金會(huì)（FRQS）合作研究項(xiàng)目，81361120245，整體水平研究EPAC/miR-124信號(hào)通路在阿爾茲海默發(fā)病中的作用和機(jī)制，100萬(wàn)元，負(fù)責(zé)人 2013.1.-2015.12.31

2014年，湖北省杰出青年基金, 2014CFA017, 組蛋白去乙酰化酶2調(diào)控AD腦內(nèi)淀粉樣蛋白生成和tau病變的機(jī)制,10萬(wàn)元，負(fù)責(zé)人，2014.1-2016.12.

2014年,  國(guó)家自然科學(xué)基金委員會(huì)海外及港澳學(xué)者合作研究基金, 81428009, 智障相關(guān)蛋白KIAA202在神經(jīng)元發(fā)育及突觸形成中的作用,20萬(wàn)元,第一參與人(境內(nèi)負(fù)責(zé)人),2015.1-2016.12.

2015年，國(guó)家自然科學(xué)基金面上項(xiàng)目，31571039，長(zhǎng)鏈非編碼RNA AK036689在阿爾茨海默病早期海馬突觸環(huán)路功能障礙中的作用，76.8萬(wàn)元，負(fù)責(zé)人，2016.1.1-2019.12.31.

2015年，國(guó)家特支計(jì)劃青年拔尖人才專(zhuān)項(xiàng)基金，190萬(wàn)元

2015年，華中科技大學(xué)首屆青年學(xué)術(shù)團(tuán)隊(duì)專(zhuān)項(xiàng)基金，60萬(wàn)元/年持續(xù)資助

2016年，國(guó)家自然科學(xué)基金重大計(jì)劃，91632114, 長(zhǎng)鏈非編碼mSYT-AS異常在阿爾茨海默病ECIIPN-CA1PV環(huán)路功能障礙中作用研究，60萬(wàn)元，負(fù)責(zé)人 2017.1.1-2019.12.31

2017年，國(guó)家自然科學(xué)基金面上項(xiàng)目動(dòng)物模型專(zhuān)項(xiàng)，81771150，運(yùn)用光遺傳可調(diào)控性轉(zhuǎn)基因小鼠模型研究基底前腦-海馬DG膽堿能神經(jīng)環(huán)路損傷在阿爾茨海默病早期模式分別障礙中的作用，80萬(wàn)元，負(fù)責(zé)人，2018.1.1-2021.12.31

2017年，國(guó)家自然科學(xué)基金創(chuàng)新群體項(xiàng)目，31721002，記憶神經(jīng)環(huán)路研究群體，1050萬(wàn)元，參與人，2018.1.1-2023.12.31

2017年，國(guó)家自然科學(xué)基金委員會(huì)（NSFC）與德國(guó)科學(xué)基金會(huì)（DFG）合作研究項(xiàng)目，81761138043，微小RNA調(diào)節(jié)網(wǎng)絡(luò)在阿爾茨海默病神經(jīng)環(huán)路功能障礙中的作用(MiRNetAD)，180萬(wàn)元，負(fù)責(zé)人，2018.1.1-2020.12.31

2018年,  國(guó)家自然科學(xué)基金委員會(huì)海外及港澳學(xué)者合作研究基金延續(xù)性項(xiàng)目, 81829002, miR-138/Nrgn信號(hào)通路在智障相關(guān)蛋白KIDLIA缺失所致自閉癥樣社交異常及突觸紊亂中的作用和機(jī)理,180萬(wàn)元,第一參與人(境內(nèi)負(fù)責(zé)人),2019.1-2022.12.

專(zhuān)利

朱鈴強(qiáng);王雄;王玉田;劉丹;黃和周。一種防治老年癡呆的藥物。專(zhuān)利號(hào)：2014106681340，授權(quán)日，2017.6.16日