朱莉萍,華中科技大學(xué)同濟醫(yī)學(xué)院二級教授、華中學(xué)者卓越首席教授、博士生導(dǎo)師。中國病理生理學(xué)會理事、中國病理生理學(xué)會缺氧和呼吸專委會委員、中國生理學(xué)會呼吸生理專委會委員。主要從事鈣信號與呼吸系疾病,特別是肺動脈高壓、肺血管損傷的發(fā)病機制研究。先后主持國家自然科學(xué)基金青年基金、青年-面上連續(xù)資助項目、面上項目、國優(yōu)秀青年基金、杰出青年基金等項目。研究論文以第一/共同第一、通訊/共同通訊發(fā)表于Circulation, Arterioscler Thromb Vasc Biol, Hypertension, J Am Heart Assoc, J Cell Sci, Biochim Biophys Acta-Mol Cell Res, Am J Physiology Lung Cell and Molecular Physiology等國際專業(yè)期刊。
Xiao R#, Liu J#, Shi L#, Zhang T, Liu J, Qiu S, Ruiz M, Dupuis J,Zhu L*, Wang L*, Wang Z*, Hu Q*. Au-modified ceria nanozyme prevents and treats hypoxia-induced pulmonary hypertension with greatly improved enzymatic activity and safety.J Nanobiotechnol. 2024;22(1):492.
Su Y#, Tan R#, Sun M#, Yuan L, Ruiz M, Dupuis J, Hu Q,Zhu L*. MiR-1249 on Endothelial Extracellular Vesicles Mediates Cigarette Smoke-Induced Pulmonary Hypertension by Inhibiting HDAC10 (Histone Deacetylase 10)-NFκB (Nuclear Factor κB)-CaSR (Calcium-Sensing Receptor) Cascade.Hypertension. 2022;79(12):2721-2732.
Xiao R, Liu J, Luo S, Yu Z, Zhang J, Lv Y, Li J, Ruiz M, Dupuis J,Hu Q*,Zhu L*. Orally-administrated mitochondria attenuate pulmonary hypertension with the aid of erythrocytes as carriers.Clin Transl Med. 2022;12(9):e1033.
Liu B#, Wei YP#, Fan X#, Hu X, Chen Z, Liu X, Xu Y, Wang L, Wang T, Ruiz M, Dupuis J, Yuan P, Liu J, Huang S,Zhu L*, Jing ZC*, Hu Q*. Calcium sensing receptor variants increase pulmonary hypertension susceptibility.Hypertension. 2022;79(7):1348-1360.
Xiao R, Luo S, Zhang T, Lv Y, Wang T, Zhang J, Su Y, Ruiz M, Dupuis J,Zhu L*,Hu Q*. Peptideblocking self-polymerization of extracellular calcium-sensing receptor attenuates hypoxia-induced pulmonary hypertension.Hypertension. 2021;78(5):1605-1616.
Zhu L, Liu F, Hao Q, Feng T, Chen Z, Luo S, Xiao R, Sun M, Zhang T, Fan X, Zeng X, He J, Yuan P, Liu J, Ruiz M, Dupuis J,Hu Q*. Dietary geranylgeranyl pyrophosphate counteracts the benefits of statin therapy in experimental pulmonary hypertension.Circulation. 2021;143(18):1775-1792.
Xiao R,Zhu L*, Su Y, Zhang J, Lu Y, Li J, Wang T, Fang J, Jing ZC, Dupuis J, Luo S,Hu Q*. Monocrotaline pyrrole induces pulmonary endothelial damage through binding to and release from erythrocytes in lung during venous blood reoxygenation.Am J Physiol Lung Cell Mol Physiol. 2019;316(5):L798-L809.
Zhu L#, Xiao R#, Zhang X, Lang Y, Liu F, Yu Z, Zhang J, Su Y, Lu Y, Wang T, Luo S, Wang J, Liu ML, Dupuis J, Jing ZC, Li T, Xiong W,Hu Q*. Spermine on endothelial extracellular vesicles mediates smoking-induced pulmonary hypertension partially through calcium-sensing receptor.Arterioscler Thromb Vasc Biol. 2019, 39(3):482-495.